Lithospermi radix, Zi Cao (racine)

Lithospermi radix

Ethnopharmacologie 

Plante de la pharmacopée chinoise utilisé traditionnellement pour la cicatrisation des plaies ainsi que des brûlures, l'eczema,  le cancer, les infections virales, effets antioxydants, anti-inflammatoire, antithrombotique, antimicrobien.

Composants

Shikonine, naphtoquinone, 

Etudes

Plus d'une centaine d'études depuis les années 1980

-maladies allergiques inflammatoires (1)

-facteur de nécrose tumoral (2)

-accélération de la cicatrisation (3)

-psoriasis (4)

1. Kim EK, Kim EY, Moon PD, Um JY, Kim HM, Lee HS, Sohn Y, Park SK, Jung HS, Sohn NW. Lithospermi radix extract inhibits histamine release and production of inflammatory cytokine in mast cells. Biosci Biotechnol Biochem. 2007 Dec;71(12):2886-92. doi: 10.1271/bbb.70208. Epub 2007 Dec 7. PMID: 18071264.

2.Chung HS, Kang M, Cho C, Park S, Kim H, Yoon YS, Kang J, Shin MK, Hong MC, Bae H. Inhibition of lipopolysaccharide and interferon-gamma-induced expression of inducible nitric oxide synthase and tumor necrosis factor-alpha by Lithospermi radix in mouse peritoneal macrophages. J Ethnopharmacol. 2005 Dec 1;102(3):412-7. doi: 10.1016/j.jep.2005.06.028. Epub 2005 Jul 28. PMID: 16054790.

3. Hsiao CY, Tsai TH, Chak KF. The molecular basis of wound healing processes induced by lithospermi radix: a proteomics and biochemical analysis. Evid Based Complement Alternat Med. 2012;2012:508972. doi: 10.1155/2012/508972. Epub 2012 Sep 17. PMID: 23024692; PMCID: PMC3457683.

4. Tan YQ, Liu JL, Bai YP, Zhang LX. Literature research of Chinese medicine recipes for the treatment of psoriasis vulgaris with blood-heat syndrome type. Chin J Integr Med. 2011 Feb;17(2):150-3. doi: 10.1007/s11655-011-0645-y. Epub 2011 Mar 9. PMID: 21390583.