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Oyster mushroom, Pleurotus ostreatus (mycelium)

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    Pleurotus ostreatus

    research began in 1932 and has since totaled 3,064 studies with more than 100 per year since 2008

    Composition :

    mycolic acid, glucose, arabinose, aspartic acid, arginine, lysine, tyrosine, alanine...Polysaccharides, B glucans

    According to these studies it was recognized that it could act positively on a large number of pathologies, of which here are some references:

    • Anti depressant (1)
    • Immunosuppressant (1)
    • Nutritional studies on the potential of proteins (2, 6)
    • Hepatoprotector (3)
    • Antioxidant (4, 7, 13, 15, 18)
    • Cancer (4, 8, 11, 16)
    • Diabetes (5, 7)
    • Cardiovascular system (5)
    • Immunomodulator (8)
    • Wastewater depollution (9,12, 14)
    • Absorption of Selenium (10)
    • Anti-inflammatory (17)
    • Antimicrobial (18)

    1. Kózka B, Nałęcz-Jawecki G, Turło J, Giebułtowicz J. Application of Pleurotus ostreatus to efficient removal of selected antidepressants and immunosuppressive agents . J Environ Manage. 2020 Nov 1;273:111131. doi: 10.1016/j.jenvman.2020.111131. Epub 2020 Aug 7. PMID: 32777642.

    2. González A, Nobre C, Simões LS, Cruz M, Loredo A, Rodríguez-Jasso RM, Contreras J, Texeira J, Belmares R. Evaluation of functional and nutritional potential of a protein concentrate from Pleurotus ostreatus mushroom . Food Chem. 2021 Jun 1;346:128884. doi: 10.1016/j.foodchem.2020.128884. Epub 2020 Dec 24. PMID: 33401088.

    3. Duan Z, Zhang Y, Zhu C, Wu Y, Du B, Ji H. Structural characterization of phosphorylated Pleurotus ostreatus polysaccharide and its hepatoprotective effect on carbon tetrachloride-induced liver injury in mice . Int J Biol Macromol. 2020 Nov 1;162:533-547. doi: 10.1016/j.ijbiomac.2020.06.107. Epub 2020 Jun 18. PMID: 32565302.

    4. Zhang Z, Zhang Y, Liu H, Wang J, Wang D, Deng Z, Li T, He Y, Yang Y, Zhong S. A water-soluble selenium-enriched polysaccharide produced by Pleurotus ostreatus: Purification, characterization, antioxidant and antitumor activities in vitro. Int J Biol Macromol. 2021 Jan 31;168:356-370. doi: 10.1016/j.ijbiomac.2020.12.070. Epub 2020 Dec 11. PMID: 33316336.

    5. Dicks L, Ellinger S. Effect of the Intake of Oyster Mushrooms (Pleurotus ostreatus) on Cardiometabolic Parameters-A Systematic Review of Clinical Trials . Nutrients. 2020 Apr 17;12(4):1134. doi:10.3390/nu12041134. PMID: 32316680; PMCID: PMC7230384.

    6. Yin C, Fan X, Ma K, Chen Z, Shi D, Yao F, Gao H, Ma A. Identification and characterization of a novel light-induced promoter for recombinant protein production in Pleurotus ostreatus . J Microbiol. 2020 Jan;58(1):39-45. doi:10.1007/s12275-020-9230-4. Epub 2019 Nov 4. PMID: 31686390.

    7. Dong Y, Zhang J, Gao Z, Zhao H, Sun G, Wang X, Jia L. Characterization and anti-hyperlipidemia effects of enzymatic residue polysaccharides from Pleurotus ostreatus . Int J Biol Macromol. 2019 May 15;129:316-325. doi: 10.1016/j.ijbiomac.2019.01.164. Epub 2019 Jan 29. PMID: 30708004.

    8. Spacek J, Vocka M, Zavadova E, Konopasek B, Petruzelka L. Immunomodulation with β-glucan from Pleurotus ostreatus in patients with endocrine-dependent breast cancer . Immunotherapy. 2022 Jan;14(1):31-40. doi: 10.2217/imt-2021-0069. Epub 2021 Nov 17. PMID: 34784798.

    9. Palli L, Castellet-Rovira F, Pérez-Trujillo M, Caniani D, Sarrà-Adroguer M, Gori R. Preliminary evaluation of Pleurotus ostreatus for the removal of selected pharmaceuticals from hospital wastewater . Biotechnol Prog. 2017 Nov;33(6):1529-1537. doi:10.1002/btpr.2520. Epub 2017 Jul 8. PMID: 28653347.

    10. Milovanović I, Brčeski I, Stajić M, Korać A, Vukojević J, Knežević A. Potential of Pleurotus ostreatus mycelium for selenium absorption . ScientificWorldJournal. 2014;2014:681834. doi:10.1155/2014/681834. Epub 2014 Jun 4. PMID: 25003145; PMCID: PMC4066853.

    11. Zhang Y, Zhang Z, Liu H, Wang D, Wang J, Liu M, Yang Y, Zhong S. A natural selenium polysaccharide from Pleurotus ostreatus: Structural elucidation, anti-gastric cancer and anti-colon cancer activity in vitro. Int J Biol Macromol. 2022 Mar 15;201:630-640. doi: 10.1016/j.ijbiomac.2022.01.101. Epub 2022 Jan 20. PMID: 35066027.

    12. Hultberg M, Ahrens L, Golovko O. Use of lignocellulosic substrate colonized by oyster mushroom (Pleurotus ostreatus) for removal of organic micropollutants from water . J Environ Manage. 2020 Oct 15;272:111087. doi: 10.1016/j.jenvman.2020.111087. Epub 2020 Jul 16. PMID: 32669250.

    13. Yokota ME, Frison PS, Marcante RC, Jorge LF, Valle JS, Dragunski DC, Colauto NB, Linde GA. Iron translocation in Pleurotus ostreatus basidiocarps: production, bioavailability, and antioxidant activity . Genet Mol Res. 2016 Feb 22;15(1). doi:10.4238/gmr.15017888. PMID: 26909996.

    14. Kumar VV, Venkataraman S, Kumar PS, George J, Rajendran DS, Shaji A, Lawrence N, Saikia K, Rathankumar AK. Laccase production by Pleurotus ostreatus using cassava waste and its application in remediation of phenolic and polycyclic aromatic hydrocarbon-contaminated lignocellulosic biorefinery wastewater . About Pollut. 2022 Sep 15;309:119729. doi: 10.1016/j.envpol.2022.119729. Epub 2022 Jul 6. PMID: 35809710.

    15. Zhang Y, Dai L, Kong X, Chen L. Characterization and in vitro antioxidant activities of polysaccharides from Pleurotus ostreatus . Int J Biol Macromol. 2012 Oct;51(3):259-65. doi: 10.1016/j.ijbiomac.2012.05.003. Epub 2012 May 10. PMID: 22579737.

    16. Gern RM, Wisbeck E, Rampinelli JR, Ninow JL, Furlan SA. Alternative medium for production of Pleurotus ostreatus biomass and potential antitumor polysaccharides. Bioresour Technol. 2008 Jan;99(1):76-82. doi: 10.1016/j.biortech.2006.11.059. Epub 2007 Feb 15. PMID: 17306976.

    17. Rivero-Pérez N, Ayala-Martínez M, Zepeda-Bastida A, Meneses-Mayo M, Ojeda-Ramírez D. Anti-inflammatory effect of aqueous extracts of spent Pleurotus ostreatus substrates in mouse ears treated with 12-O-tetradecanoylphorbol-13- acetate . Indian J Pharmacol. 2016 Mar-Apr;48(2):141-4. doi:10.4103/0253-7613.178826. PMID: 27127316; PMCID: PMC4825429.

    18. Vamanu E. In vitro antimicrobial and antioxidant activities of ethanolic extract of lyophilized mycelium of Pleurotus ostreatus PQMZ91109. Molecules. 2012 Mar 26;17(4):3653-71. doi:10.3390/molecules17043653. PMID: 22450678; PMCID: PMC6268502.

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