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Chenopodium, Chenopodium album (young shoot)

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    Chenopodium album L.

    Chenopodium is a plant that has followed man closely for millennia, it is part of what we call "plants that love men" such as nettles, elderberry, amaranth,

    In traditional Chinese medicine Chenopodium album is used to treat cough, anorexia, hemorrhoids, dysentery, as an antiviral, antifungal, anti-inflammatory, anticancer, against diarrhea and as a dewormer.

    More than 540 studies since the 1950s.

    -Reduction of oxidative stress (1)

    -Increased white blood cell count (1)

    -Hepatoprotective (1.8, 2)

    -Blood purifier, diuretic, sedative, antiscorbutic laxative and as an anthelmintic(1,2,7), antihelmintics (1, 2), anti-spermatozoa and contraceptives (2)

    -Gaba mimetic (3)

    -Anti-inflammatory, anti-arthritic (4)

    - Antioxidant (4, 9)

    -Protection against oxidative stress and heavy metal pollution) (5)

    -Breast cancer (6)

    -Wound healing and tissue regeneration (7)

    -Antimicrobial (9)

    - Anti-arthritis and antioxidant (10)

    1. Hussain S, Asrar M, Rasul A, Sultana S, Saleem U. Chenopodium album extract ameliorates carbon tetrachloride induced hepatotoxicity in rat model. Saudi J Biol Sci. 2022 May;29(5):3408-3413. doi: 10.1016/j.sjbs.2022.02.014. Epub 2022 Feb 17. PMID: 35844414; PMCID: PMC9280305.

    2. Poonia A, Upadhayay A. Chenopodium album Linn: review of nutrient value and biological properties. J Food Sci Technol. 2015 Jul;52(7):3977-85. doi:10.1007/s13197-014-1553-x. Epub 2015 Apr 7. PMID: 26139865; PMCID: PMC4486584.

    3. Choudhary N, Khatik GL, Choudhary S, Singh G, Suttee A. In vitro anthelmintic activity of Chenopodium album and in-silico prediction of mechanistic role on Eisenia foetida . Heliyon. 2021 Jan 29;7(1):e05917. doi: 10.1016/j.heliyon.2021.e05917. PMID: 33553723; PMCID: PMC7848649.

    4. Amodeo V, Marrelli M, Pontieri V, Cassano R, Trombino S, Conforti F, Statti G. Chenopodium album L. and Sisymbrium officinale (L.) Scop.: Phytochemical Content and In Vitro Antioxidant and Anti-Inflammatory Potential . Plants (Basel). 2019 Nov 15;8(11):505. doi:10.3390/plants8110505. PMID: 31731582; PMCID: PMC6918386.

    5. Jahan S, Azad T, Ayub A, Ullah A, Afsar T, Almajwal A, Razak S. Improving potency of Chenopodium album Linn. and vitamin C against mercuric chloride-induced oxidative stress in tests of Sprague Dawley rats. Environ Health Prev Med. 2019 Nov 23;24(1):62. doi:10.1186/s12199-019-0820-x. PMID: 31759394; PMCID: PMC6875164.

    6. Khoobchandani M, Ojeswi BK, Sharma B, Srivastava MM. Chenopodium album prevents progression of cell growth and enhances cell toxicity in human breast cancer cell lines. Oxid Med Cell Longev. 2009 Jul-Aug;2(3):160-5. doi: 10.4161/oxim.2.3.8837. PMID: 20592771; PMCID: PMC2763242.

    7. Said A, Naeem N, Siraj S, Khan T, Javed A, Rasheed HM, Sajjad W, Shah K, Wahid F. Mechanisms underlying the wound healing and tissue regeneration properties of Chenopodium album . 3 Biotech. 2020 Oct;10(10):452. doi:10.1007/s13205-020-02436-6. Epub 2020 Sep 25. PMID: 33062580; PMCID: PMC7519026.

    8. Ma QG, Wei RR, Zhang XD, Sang ZP, Dong JH, Lu QX, Huang HF, Guo DM, Jiang L. Tropolone derivatives with hepatoprotective and antiproliferative activities from the aerial parts of Chenopodium album Linn . Fitoterapia. 2020 Oct;146:104733. doi: 10.1016/j.fitote.2020.104733. Epub 2020 Sep 23. PMID: 32979464.

    9. Lone BA, Chishti MZ, Bhat FA, Tak H, Bandh SA, Khan A. Evaluation of anthelmintic antimicrobial and antioxidant activity of Chenopodium album . Too Anim Health Prod. 2017 Dec;49(8):1597-1605. doi:10.1007/s11250-017-1364-y. Epub 2017 Jul 22. PMID: 28735356.

    10. Arora SK, Itankar PR, Verma PR, Bharne AP, Kokare DM. Involvement of NFκB in the antirheumatic potential of Chenopodium album L., aerial parts extracts. J Ethnopharmacol. 2014 Aug 8;155(1):222-9. doi: 10.1016/j.jep.2014.05.026. Epub 2014 May 24. PMID: 24862491.

    11. Zhao T, Pan H, Feng Y, Li H, Zhao Y. Petroleum ether extract of Chenopodium album L. prevents cell growth and induces apoptosis of human lung cancer cells . Exp Ther Med. 2016 Nov;12(5):3301-3307. doi: 10.3892/etm.2016.3765. Epub 2016 Oct 3. PMID: 27882153; PMCID: PMC5103781.

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